Atypical HUS
No cure has been found out in the case of Atypical HUS. In reality, since each and every case varies, treatment cannot be standardized. Children suffering from Atypical HUS are in a greater life threatening situation. However, if the disease is diagnosed and treated early, there are chances for survival.
But the sad thing is that children with Atypical HUS often develop other complications like
Recurrence
Seizures/Neurological problems
Kidney failure
Supportive treatments will not prove effective
In spite of kidney transplantation, Atypical HUS can occur again
Hypertension in the severe form or very high blood pressure.
It is good to be aware of some older statistics. Only then, people can take the necessary steps at the right time before it is too late. There are some old websites which show a greater percentage of mortality rates. This was because Atypical HUS was a very frightening disease in those times and death rates were very high. Now it has been falling considerably and steps are further taken to lower the rates more. The cause for succeeding in dealing with death rates due to Atypical HUS is the early prognosis used by the MDs. Kidney removal is one of the treatment options but the last resort though removal of the kidney will stop all symptoms. But once the kidneys are removed, the patient needs to be on dialysis. Removal of kidneys is a very serious condition and hence it is the last option preferred.

Nevertheless, in children suffering from Atypical HUS, there is often a gradual decrease in the kidney functioning as time passes and can lead to kidney loss without removal. But in nearly half the cases, kidneys are saved.

Atypical HUS does not start violently in most of the cases. But the child just falls ill and gets fatigued, irritated, infected and finally lethargic to the point which leads to hospitalization. Supportive treatment is essential for effective prevention of any further damage. But Typical HUS starts off violently along with severe gastroenteritis accompanied sometimes by bloody diarrhea.

After the beginning stage, both Atypical and typical HUS have the same symptoms. Atypical HUS causes blood clotting and hence leads to vascular enlargement. Clotting has the potential to damage the kidneys and hence this finally leads to acute kidney failure, making the need for dialysis, kidney transplants, etc.
Symptoms can vary widely from neurological problems like seizures, coma, blindness, etc to life threatening problems. Intense intestinal and neurologic problems are indications of severe HUS. They have poor prognosis. Patients with Atypical HUS are likely to get the disease recurrently and are even more likely to get chronic kidney failure or other complications like high BP. These episodes may recur with colds and infections routinely.
 
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